Emerging approaches to study cell-cell interactions

Leiden Repository

Emerging approaches to study cell-cell interactions

Type: Doctoral Thesis
Title: Emerging approaches to study cell-cell interactions
Author: Poulcharidis, D.
Issue Date: 2020-06-03
Keywords: Cell-cell interactions
Membrane component exchange
Click Chemistry
Coiled-coil peptides
L-form bacteria
Abstract: The aim of this thesis is to study cell-cell interactions and the development of an assay to explore and quantify the exchange of membrane compounds. In the first part the rate of lipid exchange was studied, during both natural cell-cell contacts and prolonged enforced contacts. In the second part lipidated coiled-coil peptides were used to study the behaviour and potential fusogenic behaviour of these compounds on cell-wall-deficient bacteria.
Promotor: Supervisor: Kros A. Co-Supervisor: Kasteren S.I. van
Faculty: Faculty of Science
University: Leiden University
Uri: urn:isbn:9789402820225
Handle: http://hdl.handle.net/1887/92370

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