Development and evolutionary constraints in animals

Leiden Repository

Development and evolutionary constraints in animals

Type: Article / Letter to editor
Title: Development and evolutionary constraints in animals
Author: Galis, F.Metz, J.A.J.Alphen, J.J.M. van
Journal Title: Annual Review of Ecology, Evolution, and Systematics
Volume: 49
Start Page: 499
End Page: 522
Pages: 24
Issue Date: 2018
Abstract: We review the evolutionary importance of developmental mechanisms in constraining evolutionary changes in animals—in other words, developmental constraints. We focus on hard constraints that can act on macroevolutionary timescales. In particular, we discuss the causes and evolutionary consequences of the ancient metazoan constraint that differentiated cells cannot divide and constraints against changes of phylotypic stages in vertebrates and other higher taxa. We conclude that in all cases these constraints are caused by complex and highly controlled global interactivity of development, the disturbance of which has grave consequences. Mutations that affect such global interactivity almost unavoidably have many deleterious pleiotropic effects, which will be strongly selected against and will lead to long-term evolutionary stasis. The discussed developmental constraints have pervasive consequences for evolution and critically restrict regeneration capacity and body plan evolution.
Handle: http://hdl.handle.net/1887/69742
 

Files in this item

Description Size View
application/pdf Text_IR_LEI 335.2Kb View/Open Full text at publisher site

This item appears in the following Collection(s)