||This thesis utilizes a comparative perspective in analyzing the perceived differences between how people with albinism (PWA) are treated in Benin, Cameroon, The Democratic Republic of the Congo (DRC), Nigeria, South Africa, Tanzania, and Zimbabwe, by examining the variables of ethno-religious composition and socio-economic conditions in the countries. This research has shown that although the differences might be small, they are of crucial importance in how a PWA is perceived in these countries and how these notions have changed over time; from PWA being revered in pre-colonial Yorubaland and the old Kongo Kingdom, to today’s experiences of stigma and discrimination in name-calling, mutilations, and killings. Similarly, a stark contrast also exists amongst some of the countries – from PWA in Benin being revered, to PWA fearing for their lives in Tanzania due to a higher demand for PWA body parts to be used in witchcraft. Tanzania is also the African country that has garnered the most international attention for its treatment of PWA, and although the government and the state attempt to limit the extreme discrimination, it continues to persist. Nevertheless, it is important to keep in mind that the problems of stigma and discrimination as experienced by PWA are not limited to Tanzania, but exist all over the African continent.