Implantable-cardioverter-defibrillator : clinical advancements in individualized and targeted treatment

Leiden Repository

Implantable-cardioverter-defibrillator : clinical advancements in individualized and targeted treatment

Type: Doctoral Thesis
Title: Implantable-cardioverter-defibrillator : clinical advancements in individualized and targeted treatment
Author: Heijden, A.C. van der
Issue Date: 2017-02-16
Keywords: Implantable-cardioverter-defibrillator
Cardiac resynchronization therapy
Ventriculair arrhythmia
Heartfailure
Sudden cardiac death
Abstract: The beneficial effect of ICD therapy has been demonstrated in randomized trials. In the current thesis the long-term effect is evaluated in patients who received ICD therapy in contemporary clinical practice. It focusses on the effect in sub-populations that are underrepresented in randomized studies, such as women, the elderly and patients with recovery of their heart function. Prophylactic implantation of ICDs in all patients that qualify for ICD therapy according the current guidelines, will deplete the financial resources and trained personnel. Therefore, this thesis also focusses on riskstratification of ICD and CRT-D patients. Existing models developed to predict survival benefit in individual ICD patients were compared and adapted to contemporary ICD population. The current thesis is hereby providing valuable and new information to a large group of patients.
Promotor: Supervisor: M.J. Schalij Co-Supervisors: C.J.W. Borleffs; L. van Erven
Faculty: Medicine
University: Leiden
Uri: urn:isbn:9789090301679
Handle: http://hdl.handle.net/1887/46026
 

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application/pdf Cover 1.186Mb View/Open
application/pdf Full text 5.152Mb Under embargo until 2018-08-16
application/pdf Chapter 1 Gener ... and outline of the thesis 1.151Mb View/Open
application/pdf Part I 641.0Kb View/Open
application/pdf Chapter 2 1.470Mb View/Open Full text at publisher site
application/pdf Chapter 3 1.263Mb View/Open Full text at publisher site
application/pdf Chapter 4 837.2Kb View/Open Full text at publisher site
application/pdf Chapter 5 1.601Mb View/Open Full text at publisher site
application/pdf Chapter 6 1.538Mb View/Open Full text at publisher site
application/pdf Part II 641.0Kb View/Open
application/pdf Chapter 7 1.666Mb Under embargo until 2018-02-16
application/pdf Chapter 8 1.743Mb View/Open Full text at publisher site
application/pdf Part III 663.6Kb View/Open
application/pdf Chapter 9 2.318Mb View/Open Full text at publisher site
application/pdf Chapter 10 1.698Mb Under embargo until 2018-08-16
application/pdf Chapter 11 1.200Mb View/Open
application/pdf Appendix Summar ... edgements_Curriculum Vitae 1.615Mb View/Open

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