The effect of parasitic co-infections on immune responses in Gabon : particular emphasis on malaria and helminths

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The effect of parasitic co-infections on immune responses in Gabon : particular emphasis on malaria and helminths

Type: Doctoral Thesis
Title: The effect of parasitic co-infections on immune responses in Gabon : particular emphasis on malaria and helminths
Author: Ateba, Ngoa U.
Issue Date: 2016-07-07
Keywords: Malaria
Helminths
Transmission
Antibody
Cellular immunity
Cytokines
Meta-analysis
Schistosomiasis
Filaria
Abstract: The work presented in this thesis aimed at increasing our understanding of the effect of helminths on Plasmodium spp. immune response in co-infected individuals living in endemic countries. It presents data from studies conducted in rural and semi urban areas of Lambaréné (Gabon) where the burden of malaria and helminths is particularly important. Although scarce previous studies have indicated an effect of helminths on malaria outcomes and immune response to Plasmodium spp. parasite in co-infected subjects. However it is still debated how consistent is this effect across study sites and teams and what its immunological basis is.
Promotor: Supervisor: M. Yazdanbakhsh, P. G. Kremsner Co-Supervisor: A.A. Adegnika
Faculty: Medicine, Leiden University Medical Center (LUMC)
University: Leiden
Uri: urn:isbn:9789461826985
Handle: http://hdl.handle.net/1887/40905
 

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