Biological model representation and analysis

Leiden Repository

Biological model representation and analysis

Title: Biological model representation and analysis
Author: Cao, Lu
Publisher: Section Imaging & BioInformatics, Leiden Insitute of Advanced Computer Science, Faculty of Science, Leiden University
Issue Date: 2014-11-20
Keywords: Image analysis
High-throughput screening
Pattern recognition
3D reconstruction
Abstract: In this thesis, we discuss solutions of phenotype description based on the microscopy image analysis to deal with biological problems both in 2D and 3D space. Our description of patterns goes beyond conventional features and helps to visualize the unseen in feature dataset. These solutions share several common processes which are based on similar principles. Furthermore, we notice that advanced features and classier strategies can help us improve the performance of the solutions. The biological problems that we have studied include the endocytosis routing using high-throughput screening in 2D and time and 3D geometrical representation from biological structures.
Description: Promotor: J.N. Kok, Co-promotor: F.J. Verbeek
With summary in Dutch
Faculty: Faculteit der Wiskunde en Natuurwetenschappen
Citation: Cao, L., 2014, Doctoral thesis, Leiden University
Sponsor: China Scholarship Council

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application/pdf Chapter 1 Introduction 199.8Kb View/Open
application/pdf Chapter 2 17.13Mb View/Open Full text at publisher site
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application/pdf Bibliography 244.8Kb View/Open
application/pdf Summary 102.2Kb View/Open
application/pdf Summary in Dutch 102.9Kb View/Open
application/pdf List of publications_Curriculum Vitae 100.5Kb View/Open
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