Snake evolution and prospecting of snake venom

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Snake evolution and prospecting of snake venom

Title: Snake evolution and prospecting of snake venom
Author: Vonk, Freek Jacobus
Publisher: Faculty of Science, Leiden University
Issue Date: 2012-09-06
Keywords: Prospecting of snake venom
Snake evolution
Venom gene evolution
Abstract: in this thesis I have shown that snakes have undergone multiple changes in their genome and embryonic development that has provided them with the variation to which natural selection could act. This thesis provides evidence for the variable mechanisms of venom gene evolution, which presumably is much more flexible than previously thought. But it also underscores the potential use of the many different types of snake venom toxins that could be screened for use against human disorders. And most of all, I hope I have contributed towards the fact that snakes are just an incredibly interesting group of vertebrates from both the perspective of ecology and life-style, as well as from a genomic and molecular perspective. They are, and will always be, my first and true love
Description: Promotor: M.K. Richardson
With summary in Dutch
Faculty: Faculteit der Wiskunde en Natuurwetenschappen
Citation: Vonk, F.J., 2012, Doctoral thesis

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application/pdf Cover 5.582Mb View/Open
application/pdf Title page_Contents 339.3Kb View/Open
application/pdf Chapter 1 Introduction 162.3Kb View/Open
application/pdf Chapter 2 831.0Kb View/Open
application/pdf Chapter 3 957.9Kb View/Open
application/pdf Chapter 4 848.0Kb View/Open
application/pdf Chapter 5 1.181Mb View/Open
application/pdf Chapter 6 1.628Mb View/Open
application/pdf Chapter 7 Summary and discussion 172.6Kb View/Open
application/pdf Summary and discussion in Dutch 174.6Kb View/Open
application/pdf References 297.6Kb View/Open
application/pdf Curriculum Vitae_Acknowledgements 267.3Kb View/Open

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