Memory function after stress : the effects of acute stress and cortisol on memory and the inhibition of emotional distraction

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Memory function after stress : the effects of acute stress and cortisol on memory and the inhibition of emotional distraction

Type: Doctoral Thesis
Title: Memory function after stress : the effects of acute stress and cortisol on memory and the inhibition of emotional distraction
Author: Oei, Nicole Yü Lan
Publisher: Department of Clinical, Health and Neuropsychology (KGN/FSW), Leiden Institute for Brain and Cognition (LIBC), Department of Psychology, Faculty of Social and Behavioural Sciences, Leiden University
Issue Date: 2010-11-18
Keywords: Cortisol
Acute social stress
Propranolol
Emotional distraction
Working memory
Memory retrieval
fMRI
Abstract: The present thesis contains five experimental studies into the effects of stress on memory I healthy males. Hydrocortisone (and propranolol) administration or the induction of social stress are used to heighten cortisol levels, and consequently to study its effects on working memory performance and memory retrieval. In addition, by using neutral and emotional distraction during working memory, effects of cortisol on emotional distraction were investigated, also with use of functional imaging. Overall, it was consistently found that high cortisol levels, by hydrocortisone administration or induced by stress, reduced the distraction by emotional irrelevant stimuli, hence improving working memory. The current findings might be relevant for patients suffering from posttraumatic stress disorder, who typically suffer from trauma-related intrusions
Description: Promotor: P. Spinhoven, Co-promotor: B.M. Elzinga
With Summary in Dutch
Faculty: Faculteit der Sociale Wetenschappen
Citation: Oei, N.Y.L, 2010, Doctoral Thesis, Leiden University
Handle: http://hdl.handle.net/1887/16156
 

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