Gas chromatography mass spectrometry: key technology in metabolomics

Leiden Repository

Gas chromatography mass spectrometry: key technology in metabolomics

Type: Doctoral Thesis
Title: Gas chromatography mass spectrometry: key technology in metabolomics
Author: Koek, Maud Marijtje
Publisher: Faculty of Science, Leiden University
Issue Date: 2009-11-10
Keywords: Derivatization
Gas chromatography
Mass spectrometry
Metabolomics
Metabolite profiling
Metabolites
Quantitative analysis
Single cell analysis
Abstract: Metabolomics involves the unbiased quantitative and qualitative analysis of the complete set of metabolites present in cells, body fluids and tissues. Gas chromatography coupled to mass spectrometry (GC-MS) is very suitable for metabolomics analysis, as it combines high separation power with sensitive and selective mass detection. This thesis is dedicated to the development of reliable quantitative GC-MS based methods for metabolomics analysis.
Description: Promotor: Th. Hankemeier
With summary in Dutch
Faculty: LUMC
Citation: Koek, M.M., 2009, Doctoral thesis, Leiden University
ISBN: 9789074538695
Sponsor: TNO Kwaliteit van Leven
Handle: http://hdl.handle.net/1887/14328
 

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application/pdf Title page_Contents 77.28Kb View/Open
application/pdf Chapter 1 General introduction and scope 2.503Mb View/Open
application/pdf Chapter 2 419.5Kb View/Open
application/pdf Chapter 3 450.5Kb View/Open Full text at publisher site
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application/pdf Chapter 8 Conclusions and perspectives 274.0Kb View/Open
application/pdf Summary 61.71Kb View/Open
application/pdf Summary in Dutch 63.22Kb View/Open
application/pdf Afterword_Curriculum vitae_List of publications 84.28Kb View/Open
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