Dimeric ligands for GPCRs involved in human reproduction: synthesis and biological evaluation

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Dimeric ligands for GPCRs involved in human reproduction: synthesis and biological evaluation

Type: Doctoral Thesis
Title: Dimeric ligands for GPCRs involved in human reproduction: synthesis and biological evaluation
Author: Bonger, Kimberly Michelle
Publisher: Department Bioorganische Synthese, Leiden Institute of Chemistry, Faculty of Science, Leiden University
Issue Date: 2008-12-19
Keywords: Dimeric ligands
Gonadotropin receptor
Follicle stimulating hormone receptor
Luteinizing hormone receptor
Reproduction GPCRs
Abstract: Dimeric ligands for G-protein coupled receptors that are involved in human reproduction, namely the gonadotropin releasing hormone receptor, the luteinizing hormone receptor and the follicle-stimulating hormone receptor, were synthesized and biologically evaluated.
Description: Promotores: H.S. Overkleeft, G.A. van der Marel
With summary in Dutch
Faculty: Faculteit der Wiskunde en Natuurwetenschappen
Citation: Bonger, K.M., 2008, Doctoral thesis, Leiden University
Sponsor: The project has been financially supported by the Council for Chemical Sciences of the Netherlands Organization for Scientific Research (CW-NWO) and the Schering-Plough Research Institute (Oss).
Handle: http://hdl.handle.net/1887/13368
 

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application/pdf Title page_Table of contents_List of abbreviations 49.43Kb View/Open
application/pdf Chapter 1 852.4Kb View/Open
application/pdf Chapter 2 206.1Kb View/Open Full text at publisher site
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application/pdf Chapter 8 220.8Kb View/Open
application/pdf Chapter 9 166.2Kb View/Open
application/pdf Summary and future prospects 89.17Kb View/Open
application/pdf Summary in Dutch 34.71Kb View/Open
application/pdf List of publications_Curriculum vitae_Afterword 45.22Kb View/Open
application/pdf Propositions 35.46Kb View/Open

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