Quality assurance in surgical oncology

Leiden Repository

Quality assurance in surgical oncology

Type: Doctoral Thesis
Title: Quality assurance in surgical oncology
Author: Peeters, Koen Clemens Maria Johannes
Publisher: Department of Surgery, Faculty of Medicine / Leiden University Medical Center (LUMC), Leiden University
Issue Date: 2007-03-28
Keywords: Anastomotic leakage
Gastric cancer
Minimal residual disease
Rectal cancer
Abstract: Quality of surgical procedures in the treatment of cancer patients is of utmost importance. This thesis focuses on two large prospective randomised trials on gastric and rectal cancer. Important feature in both trials was the standardisation and quality control of surgery, enabling the reliable assessment of the rol of adjunctive therapies. The trial on gastric cancer showed no benefitit of extensive lymph node dissection in gastric cancer. However, if postoperative morbidity is reduced, extended surgery may be of benefit. Various ways of reducing the likelihood of postoperative complications are considered. The trial on rectal cancer patients showed that short term preoperative radiotherapy is capable of reducing the risk of local recurrence, which however does not lead to improvement of survival. Moreover, there are important side effects of radiotherapy, the most important one being the increased incidence of fecal incontinence in irradiated patients.
Description: Promotor: C.J.H. van de Velde
With summary in Dutch
Faculty: LUMC
Citation: Peeters, K.C.M.J., 2007, Doctoral thesis, Leiden University
ISBN: 9789085592785
Sponsor: Tyco Health Care Smiths Medical Pfizer BV Amgen BV Johnson en Johnson BV Jansen-Cilag BV
Handle: http://hdl.handle.net/1887/11462

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